/* AMS source-bound clinical explorer: quiet medical blue, subtle Hue violet, no gradients. */
.ams-app [data-ams-lookup="protocols"]{min-width:0}
.ams-app .ams-kb-explorer{--kb-ink:#1d3748;--kb-deep:#0b617c;--kb-teal:#0784a0;--kb-soft:#eff8fa;--kb-line:#d4e4e9;--kb-purple:#765395;max-width:1500px;margin:auto;color:var(--kb-ink);font-family:inherit;overflow-wrap:anywhere}
.ams-app .ams-kb-explorer *{box-sizing:border-box}
.ams-app .ams-kb-explorer button{font:inherit;cursor:pointer}
.ams-app .ams-kb-explorer button:focus-visible,.ams-app .ams-kb-explorer input:focus-visible,.ams-app .ams-kb-explorer a:focus-visible{outline:3px solid #57abc3;outline-offset:2px}
.ams-app .ams-kb-explorer [hidden]{display:none!important}
.ams-app .ams-kb-searchbar{margin:0 0 15px;border:1px solid var(--kb-line);border-radius:13px;background:#f7fbfc;padding:16px 20px}
.ams-app .ams-kb-searchbar>label{display:block;color:#23566a;font-size:12.5px;font-weight:750;margin:0 0 7px}
.ams-app .ams-kb-searchline{display:flex;align-items:center;gap:10px;padding:5px 6px 5px 14px;border:1px solid #b9d8e1;border-radius:10px;background:#fff;box-shadow:0 2px 8px #175d7510}
.ams-app .ams-kb-search-icon{font-size:27px;line-height:1;color:#4493a5;font-weight:400}
.ams-app .ams-kb-searchline input{flex:1;min-width:0;width:100%;border:0!important;outline:0!important;box-shadow:none!important;font-family:inherit;font-size:15px;color:#203d4c;background:transparent!important;padding:9px 2px;min-height:41px}
.ams-app .ams-kb-searchline:focus-within{border-color:#178aa6;box-shadow:0 0 0 3px #0b88a31c}
.ams-app .ams-kb-searchline input::placeholder{color:#7b929d}
.ams-app .ams-kb-searchline button{border:1px solid #c6dce3;border-radius:8px;background:#eef6f9;color:#356779;min-height:36px;padding:6px 14px;font-size:12.5px;font-weight:650}
.ams-app .ams-kb-clear-icon{display:none}
.ams-app .ams-kb-searchline button:hover{background:#deedf3}
.ams-app .ams-kb-example-row{display:flex;flex-wrap:wrap;align-items:center;gap:7px;margin-top:11px}
.ams-app .ams-kb-example-row>span{font-size:11.5px;color:#617f8c;margin-right:3px}
.ams-app .ams-kb-example-row button{min-height:27px;border:1px solid #d4e3e8;border-radius:20px;padding:4px 11px;background:#fff;font-size:11.5px;color:#436a7c;font-weight:600}
.ams-app .ams-kb-example-row button:hover{color:#086881;border-color:#8fbeca;background:#eff9fb}
.ams-app .ams-kb-layout{display:grid;grid-template-columns:minmax(260px,.72fr) minmax(0,1.9fr);gap:15px;align-items:stretch;min-width:0}
.ams-app .ams-kb-left{min-width:0;display:flex;flex-direction:column;gap:12px}
.ams-app .ams-kb-mobile-toggle{display:none}
.ams-app .ams-kb-left-head{background:#fff;border:1px solid var(--kb-line);border-radius:12px;padding:16px 17px 13px}
.ams-app .ams-kb-left-head h2{font-size:16px;line-height:1.4;font-weight:750;color:#164f65;margin:0 0 2px}
.ams-app .ams-kb-left-head p{font-size:11.5px;color:#67818d;margin:0}
.ams-app .ams-kb-suggestions{background:#f4f9fa;border:1px solid var(--kb-line);border-radius:12px;padding:10px;max-height:470px;overflow:auto;scrollbar-width:thin;min-height:140px}
.ams-app .ams-kb-result-btn{width:100%;min-width:0;display:block;text-align:left;border:1px solid #dbe6eb!important;background:#fff!important;color:#2c4a59!important;border-radius:9px!important;padding:13px 14px!important;min-height:0!important;margin:0 0 8px!important;box-shadow:none!important;line-height:1.45}
.ams-app .ams-kb-result-btn:last-child{margin-bottom:0!important}
.ams-app .ams-kb-result-btn:hover{border-color:#8fc3d0!important;background:#f7fcfd!important;color:#155c73!important}
.ams-app .ams-kb-result-btn.is-active{background:#e8f6f8!important;border-color:#1888a1!important;box-shadow:none!important}
.ams-app .ams-kb-result-btn strong{display:block;color:#24495c;font-size:13.4px;font-weight:720;line-height:1.47;white-space:normal}
.ams-app .ams-kb-result-btn small,.ams-app .ams-kb-result-btn span:not(.ams-kb-result-number){display:block;font-size:11.5px;line-height:1.4;color:#758b96;font-weight:450;margin-top:4px}
.ams-app .ams-kb-result-btn .ams-kb-result-disease{color:#755491!important;letter-spacing:.02em;font-weight:650;margin:0 0 5px}
.ams-app .ams-kb-best-tag{display:inline-flex;align-items:center;margin-top:8px;border:1px solid #b8dce5;border-radius:5px;background:#eaf7f9;padding:3px 7px;color:#106e87;font-size:10.5px;font-style:normal;font-weight:700}
.ams-app .ams-kb-result-number{display:inline-block;background:#eaf3f6;color:#1d718a;border-radius:6px;padding:2px 6px;margin:0 0 7px;font-size:10px;font-weight:750}
.ams-app .ams-kb-no-match{padding:22px 14px;font-size:13px;line-height:1.6;color:#59717f}
.ams-app .ams-kb-no-match strong{display:block;color:#244b60;margin-bottom:5px}
.ams-app .ams-kb-no-match p{margin:0}
.ams-app .ams-kb-outline{background:#fff;border:1px solid var(--kb-line);border-radius:12px;overflow:hidden}
.ams-app .ams-kb-outline-heading{padding:14px 15px 12px;border-bottom:1px solid #e2ebef;background:#f8fbfc}
.ams-app .ams-kb-outline-heading h3{font-size:13px;margin:0 0 3px;color:#275b70;font-weight:750}
.ams-app .ams-kb-outline-heading small{display:block;color:#765a91;font-size:11px;line-height:1.45}
.ams-app .ams-kb-outline-list{max-height:330px;overflow:auto;padding:8px;scrollbar-width:thin}
.ams-app .ams-kb-outline-list button{display:block;text-align:left;width:100%;min-height:0!important;font-size:12px;line-height:1.5;border:0;background:transparent;color:#466a7c;padding:7px 9px;border-radius:6px;font-weight:550}
.ams-app .ams-kb-outline-list button:hover{background:#eaf6f8;color:#076980}
.ams-app .ams-kb-outline-list button.is-active{background:#e6f2f7;color:#075f79;font-weight:750}
.ams-app .ams-kb-outline-list .ams-kb-outline-level-3{padding-left:19px;font-size:11.8px;color:#677e8b}
.ams-app .ams-kb-right{min-width:0;min-height:690px;max-height:min(79vh,1050px);overflow-y:auto;overscroll-behavior:contain;scrollbar-width:thin;border:1px solid #d2e3e9;border-radius:13px;background:#fff;box-shadow:0 5px 22px #12445c0d;outline-offset:3px;scroll-behavior:smooth}
.ams-app .ams-kb-welcome{min-height:630px;display:flex;flex-direction:column;justify-content:center;align-items:center;text-align:center;padding:45px;color:#6f8894}
.ams-app .ams-kb-welcome-mark{display:flex;justify-content:center;align-items:center;width:76px;height:76px;border:1px solid #cce7ed;border-radius:22px;background:#e8f7fa;color:#1787a1;font-size:42px;font-weight:300;margin-bottom:22px}
.ams-app .ams-kb-welcome h2{font-size:19px;color:#23566b;margin:0 0 10px}
.ams-app .ams-kb-welcome p{max-width:470px;font-size:13.5px;line-height:1.65;margin:0}
.ams-app .ams-kb-detail-top{display:flex;justify-content:space-between;align-items:flex-start;flex-wrap:wrap;gap:16px;padding:25px 26px 21px;border-bottom:1px solid #dfeaf0;background:#fbfdfe}
.ams-app .ams-kb-detail-top>div:first-child{flex:1 1 420px;min-width:0}
.ams-app .ams-kb-source-label{font-size:10.5px!important;letter-spacing:1px;color:#775395!important;font-weight:750;margin:0 0 7px!important}
.ams-app .ams-kb-mobile-result-label{display:none}
.ams-app .ams-kb-detail-top h2{font-size:clamp(20px,1.8vw,27px);line-height:1.3;font-weight:800;color:#0e526d;letter-spacing:-.02em;margin:0 0 9px}
.ams-app .ams-kb-detail-path{color:#1b7890;font-size:12.5px;font-weight:690;line-height:1.55}
.ams-app .ams-kb-detail-path-short{display:none}
.ams-app .ams-kb-detail-tools summary{display:none}
.ams-app .ams-kb-detail-actions{display:flex;flex-wrap:wrap;gap:8px;align-items:center}
.ams-app .ams-kb-detail-actions button{font-size:12px;min-height:35px;padding:8px 12px;border-radius:8px;border:1px solid #b6d8e0;background:#e9f6f9;color:#116e88;font-weight:680}
.ams-app .ams-kb-detail-actions button:last-child{background:#fff;color:#596b84;border-color:#d6dce8}
.ams-app .ams-kb-detail-actions button:hover{border-color:#16839d;background:#daf0f5}
.ams-app .ams-kb-readable-note{margin:18px 26px 5px;border:1px solid #cde6ec;border-radius:7px;background:#eff8fa;padding:11px 13px;color:#4a6b7c;font-size:12.5px;line-height:1.6}
.ams-app .ams-kb-source-content{padding:8px 26px 26px;font-size:14.5px;line-height:1.76;color:#263d4b}
.ams-app .ams-kb-source-content h3{font-size:20px;line-height:1.4;color:#075e78;border-bottom:1px solid #d7e9ee;margin:27px 0 15px;padding:0 0 8px;font-weight:770}
.ams-app .ams-kb-source-content h4{font-size:16.7px;line-height:1.45;color:#654987;margin:24px 0 9px;font-weight:750}
.ams-app .ams-kb-source-content h5{font-size:14.8px;line-height:1.45;color:#275a71;margin:21px 0 7px;font-weight:720}
.ams-app .ams-kb-source-content p{white-space:pre-wrap;margin:7px 0 12px;overflow-wrap:anywhere}
.ams-app .ams-kb-source-content .ams-kb-list{padding-left:15px}
.ams-app .ams-kb-source-content img{display:block;max-width:100%;height:auto;margin:15px auto}
.ams-app .ams-kb-source-content .ams-kb-table-scroll{max-width:100%;overflow-x:auto;border:1px solid #cddfe7;border-radius:9px;margin:14px 0 19px;scrollbar-width:thin}
.ams-app .ams-kb-source-content .ams-kb-table{min-width:640px;width:100%;border-collapse:separate;border-spacing:0;table-layout:auto;font-size:12.4px;line-height:1.5}
.ams-app .ams-kb-source-content .ams-kb-table td{padding:9px 11px;min-width:80px;max-width:445px;border-right:1px solid #d6e4e9;border-bottom:1px solid #d6e4e9;vertical-align:top;overflow-wrap:break-word}
.ams-app .ams-kb-source-content .ams-kb-table tr:first-child{background:#e9f5f8;font-weight:700}
.ams-app .ams-kb-source-content .ams-kb-table tr:nth-child(even){background:#f7fafc}
.ams-app .ams-kb-source-content .ams-kb-table td:last-child{border-right:0}
.ams-app .ams-kb-source-content .ams-kb-table tr:last-child td{border-bottom:0}
.ams-app .ams-kb-source-content .ams-kb-table p{margin:0 0 4px}
.ams-app .ams-kb-source-content :target{background:#edf9fb;outline:2px solid #3b9bb1;outline-offset:3px;scroll-margin-top:130px}
.ams-app .ams-kb-related{margin:0 26px 23px;padding:15px 16px;border:1px solid #d3e5ea;border-radius:10px;background:#f8fbfc;color:#486477}
.ams-app .ams-kb-related summary{font-size:13px;font-weight:750;cursor:pointer;color:#165f75}
.ams-app .ams-kb-related h3{font-size:14px;color:#165f75;margin:0 0 5px}
.ams-app .ams-kb-related p{font-size:12px;margin:0 0 10px}
.ams-app .ams-kb-related>a{font-size:12px;margin:0 15px 0 0;color:#0a7c97;text-decoration:none;font-weight:700}
.ams-app .ams-kb-related-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(min(100%,205px),1fr));gap:9px;margin-top:15px}
.ams-app .ams-kb-drug-card{border:1px solid #dde8ee;background:#fff;border-radius:8px;padding:10px 12px}
.ams-app .ams-kb-drug-card strong{font-size:12.3px;display:block;margin-bottom:6px;color:#294657}
.ams-app .ams-kb-drug-card a{display:inline-block;margin:0 11px 4px 0;font-size:11.7px;color:#08738d;font-weight:700;text-decoration:none}
.ams-app .ams-kb-related a:hover{text-decoration:underline}
.ams-app .ams-kb-source-foot{margin:0 26px 28px;padding-top:10px;border-top:1px solid #e2eaee;font-size:11.5px;color:#6f8792;line-height:1.5}
.ams-app .ams-kb-footer-note{font-size:11.5px;color:#758992;line-height:1.5;margin:14px 3px 0}
@media(max-width:1000px){
  .ams-app .ams-kb-layout{grid-template-columns:minmax(235px,.78fr) minmax(0,1.65fr);gap:11px}
  .ams-app .ams-kb-detail-top{padding:20px}
  .ams-app .ams-kb-source-content{padding:7px 20px 22px}
  .ams-app .ams-kb-readable-note,.ams-app .ams-kb-related{margin-left:20px;margin-right:20px}
}
@media(max-width:700px){
  .ams-app .ams-kb-searchbar{padding:10px 11px;margin:0 0 7px;border-radius:10px}
  .ams-app .ams-kb-searchbar>label{font-size:12px;margin-bottom:5px}
  .ams-app .ams-kb-searchline{padding:3px 4px 3px 10px;gap:4px;border-radius:8px}
  .ams-app .ams-kb-search-icon{display:none}
  .ams-app .ams-kb-searchline input{font-size:16px;min-height:39px;padding:6px 3px}
  .ams-app [data-ams-lookup="protocols"] .ams-kb-searchline button{padding:0 9px;min-height:34px;font-size:21px;line-height:1}
  .ams-app .ams-kb-clear-text{display:none}
  .ams-app .ams-kb-clear-icon{display:inline}
  .ams-app .ams-kb-example-row{display:none}
  .ams-app .ams-kb-layout{grid-template-columns:1fr;gap:7px}
  .ams-app .ams-kb-left{gap:5px}
  .ams-app .ams-kb-mobile-toggle{display:flex;align-items:center;gap:7px;width:100%;min-height:39px;padding:7px 12px;border:1px solid #cde0e8;border-radius:9px;background:#eff8fa;color:#15677e;font-size:12.5px;font-weight:700;text-align:left}
  .ams-app .ams-kb-mobile-toggle small{font-size:11px;font-weight:600;color:#66828f;margin-left:auto}
  .ams-app .ams-kb-toggle-chevron{font-size:19px;line-height:1;transition:transform .16s}
  .ams-app .ams-kb-left.is-mobile-expanded .ams-kb-toggle-chevron{transform:rotate(180deg)}
  .ams-app .ams-kb-left-head{display:none}
  .ams-app .ams-kb-suggestions{display:none;max-height:min(45vh,340px);min-height:0;padding:7px}
  .ams-app .ams-kb-left.is-mobile-expanded .ams-kb-suggestions{display:block}
  .ams-app .ams-kb-outline{display:none}
  .ams-app .ams-kb-right{min-height:250px;max-height:none;overflow:visible;scroll-margin-top:7px;border-radius:10px}
  .ams-app .ams-kb-welcome{min-height:210px;padding:24px 18px}
  .ams-app .ams-kb-welcome-mark{width:46px;height:46px;font-size:26px;border-radius:13px;margin-bottom:10px}
  .ams-app .ams-kb-welcome h2{font-size:17px}
  .ams-app .ams-kb-detail-top{padding:13px 14px 10px;gap:5px}
  .ams-app .ams-kb-detail-top>div:first-child{flex:1 1 100%}
  .ams-app .ams-kb-source-label{display:none}
  .ams-app .ams-kb-mobile-result-label{display:block;color:#087c95;font-size:10px;font-weight:800;letter-spacing:.06em;margin:0 0 5px!important}
  .ams-app .ams-kb-detail-top h2{font-size:18px;margin:0 0 4px;letter-spacing:0;line-height:1.35}
  .ams-app .ams-kb-detail-path{font-size:12px;line-height:1.45}
  .ams-app .ams-kb-detail-path-long{display:none}
  .ams-app .ams-kb-detail-path-short{display:inline}
  .ams-app .ams-kb-detail-tools{width:100%;text-align:right}
  .ams-app [data-ams-lookup="protocols"] .ams-kb-detail-tools summary{display:inline-block;list-style:none;cursor:pointer;min-height:32px;font-size:11px;font-weight:650;padding:5px 9px;background:#f4f8fa;color:#426a7d;border:1px solid #d7e6ec;border-radius:6px}
  .ams-app .ams-kb-detail-tools summary::-webkit-details-marker{display:none}
  .ams-app .ams-kb-detail-actions{justify-content:flex-end;padding:8px 0 1px;gap:6px}
  .ams-app .ams-kb-detail-actions button{font-size:11px;min-height:32px;padding:6px 9px}
  .ams-app .ams-kb-readable-note{display:none}
  .ams-app .ams-kb-related{margin:9px 13px 15px;padding:11px 12px}
  .ams-app .ams-kb-source-content{padding:0 14px 17px;font-size:14px;line-height:1.67}
  .ams-app .ams-kb-source-content h3{font-size:17px;margin:13px 0 9px;padding-bottom:6px}
  .ams-app .ams-kb-source-content h4{font-size:15.5px;margin:14px 0 7px}
  .ams-app .ams-kb-source-content h5{font-size:14.2px;margin:12px 0 6px}
  .ams-app .ams-kb-source-content .ams-kb-table{min-width:520px;font-size:12px}
  .ams-app .ams-kb-source-foot{margin:0 14px 17px}
  .ams-app .ams-kb-footer-note{display:none}
  .ams-app .ams-kb-result-btn{padding:9px 11px!important;margin-bottom:6px!important}
}
@media print{
  .ams-app .ams-kb-searchbar,.ams-app .ams-kb-left,.ams-app .ams-kb-detail-actions,.ams-app .ams-kb-footer-note{display:none!important}
  .ams-app .ams-kb-layout{display:block}
  .ams-app .ams-kb-right{max-height:none;overflow:visible;border:0;box-shadow:none}
  .ams-app .ams-kb-source-content .ams-kb-table-scroll{overflow:visible}
}