.ams-sp{--sp-ink:#16324a;--sp-blue:#0b6480;--sp-border:#d9e4eb;color:var(--sp-ink);font:16px/1.65 system-ui,-apple-system,"Segoe UI",sans-serif;max-width:1240px;margin:0 auto;overflow-wrap:anywhere}
.ams-sp *{box-sizing:border-box}.ams-sp [hidden]{display:none!important}.ams-sp h1,.ams-sp h2,.ams-sp h3,.ams-sp h4,.ams-sp p{margin:0 0 12px}.ams-sp h1{font-size:30px;line-height:1.3;color:#fff}.ams-sp h2{font-size:22px;line-height:1.45}.ams-sp h3{font-size:18px;line-height:1.5}.ams-sp h4{font-size:17px;line-height:1.5}.ams-sp p:last-child{margin-bottom:0}.ams-sp .sp-header{padding:30px;border-radius:18px;background:linear-gradient(120deg,#124c66,#08798a);color:#e9f7fb;display:flex;gap:24px;align-items:flex-start}.ams-sp .sp-header>div{flex:1}.ams-sp .sp-eyebrow{font-size:12px;font-weight:750;letter-spacing:1.4px;margin-bottom:10px}.ams-sp .sp-edition{border:1px solid #73b8c8;border-radius:30px;padding:5px 12px;font-size:12px;white-space:nowrap}.ams-sp .sp-notice{font-size:14px;color:#526777;padding:12px 4px}.ams-sp .sp-search-panel,.ams-sp .sp-context,.ams-sp .sp-reference{background:#fff;border:1px solid var(--sp-border);border-radius:14px;padding:22px;margin:0 0 18px}.ams-sp label{display:block;font-size:14px;font-weight:650}.ams-sp input:not([type=checkbox]),.ams-sp select{display:block;width:100%;border:1px solid #acbecb;background:white;color:var(--sp-ink);border-radius:8px;min-height:46px;padding:10px 12px;font:inherit;font-size:16px;margin:6px 0 0;max-width:100%;min-width:0}.ams-sp input[type=checkbox]{accent-color:#08778a;width:18px;height:18px;flex:0 0 18px;margin:3px 0 0}.ams-sp input:focus-visible,.ams-sp select:focus-visible,.ams-sp button:focus-visible,.ams-sp summary:focus-visible{outline:3px solid #46a5ce;outline-offset:3px}.ams-sp button{font:inherit;font-size:14px;font-weight:650;cursor:pointer;background:#eef6f9;color:#124f69;border:1px solid #c9dce6;border-radius:8px;min-height:42px;padding:9px 14px;line-height:1.5;white-space:normal}.ams-sp button:hover{background:#dfeff5}.ams-sp .sp-search-line{display:flex;gap:10px;align-items:center}.ams-sp .sp-search-line input{margin-top:6px;flex:1}.ams-sp .sp-search-line button{margin-top:6px}.ams-sp .sp-muted,.ams-sp .sp-caption{font-size:13px;color:#536b7c}.ams-sp #sp-search-help{margin:8px 0 12px}.ams-sp .sp-examples{display:flex;gap:8px;flex-wrap:wrap}.ams-sp .sp-examples button{border-radius:24px;padding:5px 13px;min-height:34px;font-size:13px}.ams-sp .sp-filter-line{display:flex;gap:20px;align-items:flex-end;margin-top:18px}.ams-sp .sp-filter-line label{flex:1;max-width:440px}.ams-sp #sp-count{font-size:13px;padding-bottom:10px;margin:0}.ams-sp summary{cursor:pointer;font-weight:700;line-height:1.6}.ams-sp .sp-context[open]>summary{margin-bottom:18px}.ams-sp .sp-fields{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px}.ams-sp .sp-checks{display:flex;flex-wrap:wrap;gap:12px 24px;margin:18px 0}.ams-sp .sp-checks label{display:flex;align-items:flex-start;gap:8px;font-weight:500}.ams-sp .sp-risk{border-top:1px solid var(--sp-border);padding-top:14px;margin:16px 0}.ams-sp .sp-risk .sp-fields{margin:16px 0}.ams-sp .sp-risk-factors{display:grid;grid-template-columns:repeat(2,minmax(0,1fr))}.ams-sp .sp-subtle{background:#fff;margin:2px 0 10px}.ams-sp .sp-callout{background:#eff7fb;border:1px solid #c3dee9;border-radius:8px;padding:13px 16px;margin-bottom:12px;font-size:14px}.ams-sp .sp-warning{background:#fff8e9;border-color:#e8ce90;color:#69490d}.ams-sp .sp-danger{background:#fff0ef;border-color:#edbfba;color:#892b24}.ams-sp .sp-layout{display:grid;grid-template-columns:minmax(250px,0.85fr) minmax(0,2fr);gap:20px;align-items:start;margin:18px 0}.ams-sp .sp-results-panel{background:#f4f8fa;border:1px solid var(--sp-border);border-radius:14px;padding:16px;min-width:0}.ams-sp .sp-results-panel>h2{font-size:16px;margin-bottom:12px}.ams-sp #sp-results{max-height:760px;overflow:auto;padding:2px 5px 3px 2px;scrollbar-width:thin}.ams-sp .sp-result{display:block;width:100%;text-align:left;background:#fff;margin:0 0 9px;padding:13px;border:1px solid #d9e3e9;border-radius:9px;font-weight:400}.ams-sp .sp-result small{display:block;color:#527183;font-size:11px;margin-bottom:5px}.ams-sp .sp-result strong{font-size:14px;font-weight:650;display:block}.ams-sp .sp-result.is-active{border:2px solid #147b95;background:#eaf6fa;padding:12px}.ams-sp .sp-fuzzy{display:block;font-size:11px;color:#8a5c0e;margin-top:6px}.ams-sp .sp-detail{min-width:0;background:#fff;border:1px solid var(--sp-border);border-radius:14px;padding:24px;outline-offset:4px}.ams-sp .sp-detail-top{border-bottom:1px solid var(--sp-border);margin-bottom:20px}.ams-sp .sp-detail-top .sp-eyebrow{color:#097487}.ams-sp .sp-empty{padding:36px 12px;text-align:center;color:#536b7c}.ams-sp .sp-empty>span{display:block;font-size:56px;color:#76a1b4;line-height:1;margin-bottom:24px}.ams-sp .sp-regimens{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:14px;margin-bottom:12px}.ams-sp .sp-regimens>section{background:#f7f9fb;border:1px solid var(--sp-border);border-radius:9px;padding:16px}.ams-sp .sp-regimens>.sp-preferred{background:#eef8f7;border-color:#8fc6c4}.ams-sp .sp-regimens h3{font-size:15px}.ams-sp .sp-verbatim{white-space:pre-wrap;overflow-wrap:anywhere}.ams-sp .sp-dose-heading{display:flex;justify-content:space-between;align-items:center;gap:12px;margin:24px 0 12px}.ams-sp .sp-dose-heading h3{margin:0}.ams-sp .sp-dose-heading>span{font-size:12px;color:#617a8a}.ams-sp .sp-dose-cards{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px;margin-bottom:12px}.ams-sp .sp-dose-card{border:1px solid var(--sp-border);padding:14px;border-radius:9px}.ams-sp .sp-dose-card h4{color:#11647c}.ams-sp dl{margin:0;font-size:13px}.ams-sp dt{color:#617786;font-size:12px;margin-top:8px}.ams-sp dd{margin:1px 0 0;white-space:pre-wrap}.ams-sp .sp-drug-warning{color:#956018;font-size:12px;margin-top:10px}.ams-sp .sp-calculator{border:1px solid #a9cdd8;border-radius:10px;background:#f6fbfd;padding:18px;margin:24px 0}.ams-sp .sp-calculator .sp-fields{grid-template-columns:repeat(2,minmax(0,1fr));margin-bottom:16px}.ams-sp .sp-calculated{font-size:14px;margin-bottom:14px}.ams-sp .sp-actions{margin-top:20px;display:flex;gap:12px;align-items:center;flex-wrap:wrap}.ams-sp .sp-actions span{font-size:13px}.ams-sp .sp-reference[open]>summary{margin-bottom:18px}.ams-sp .sp-reference select{max-width:620px;margin-bottom:20px}.ams-sp .sp-source-table{overflow:auto;margin:18px 0}.ams-sp table{border-collapse:collapse;width:100%;min-width:640px;font-size:13px}.ams-sp th,.ams-sp td{padding:12px;border:1px solid #cbd9e1;text-align:left;white-space:pre-wrap;vertical-align:top}.ams-sp th{background:#eaf3f7}.ams-sp .sp-footer{text-align:center;color:#667c8b;font-size:12px;padding:18px}.ams-sp .sp-pharmacy{margin:18px 0;border-top:1px solid #d9e4eb;padding-top:15px}.ams-sp .sp-pharmacy details{border:1px solid var(--sp-border);padding:12px;border-radius:8px;margin:10px 0}.ams-sp .sp-pharmacy dl{margin-top:14px}.ams-sp .sp-pharmacy dt{font-weight:700;color:#244e66}.ams-sp .sp-pharmacy dd{margin-bottom:12px}
@media(max-width:900px){.ams-sp .sp-layout{grid-template-columns:minmax(210px,0.8fr) minmax(0,1.5fr)}.ams-sp .sp-regimens,.ams-sp .sp-dose-cards{grid-template-columns:1fr}.ams-sp .sp-fields{grid-template-columns:repeat(2,minmax(0,1fr))}.ams-sp .sp-header{padding:24px}.ams-sp .sp-edition{display:none}}
@media(max-width:620px){.ams-sp h1{font-size:24px}.ams-sp h2{font-size:20px}.ams-sp .sp-header{padding:20px}.ams-sp .sp-search-panel,.ams-sp .sp-context,.ams-sp .sp-reference,.ams-sp .sp-detail{padding:16px}.ams-sp .sp-layout{grid-template-columns:1fr}.ams-sp #sp-results{max-height:340px}.ams-sp .sp-fields,.ams-sp .sp-calculator .sp-fields,.ams-sp .sp-risk-factors{grid-template-columns:1fr}.ams-sp .sp-search-line{flex-wrap:wrap}.ams-sp .sp-search-line input{flex-basis:100%}.ams-sp .sp-filter-line{display:block}.ams-sp #sp-count{padding-top:10px}.ams-sp .sp-checks{display:grid;grid-template-columns:1fr}.ams-sp .sp-context summary>.sp-muted{display:block}.ams-sp .sp-calculator{padding:14px}.ams-sp .sp-edition{display:none}}
@media print{.ams-sp .sp-search-panel,.ams-sp .sp-results-panel,.ams-sp .sp-actions,.ams-sp .sp-reference,.ams-sp .sp-examples{display:none}.ams-sp .sp-layout{display:block}.ams-sp .sp-header{background:#fff;color:#16324a;border:1px solid #aaa}.ams-sp h1{color:#16324a}.ams-sp .sp-detail{border:0;padding:0}.ams-sp .sp-dose-card{break-inside:avoid}}
.ams-sp .sp-results-toggle{display:none}
.ams-sp .sp-auto-badge{font-size:11px;font-weight:750;color:#096f84;margin:0 0 5px}
@media screen and (max-width:700px){
  .ams-sp{display:flex;flex-direction:column;gap:8px;font-size:14px;line-height:1.55}
  .ams-sp .sp-header,.ams-sp .sp-notice,.ams-sp .sp-footer{display:none}
  .ams-sp .sp-search-panel{order:1;margin:0;padding:11px 12px;border-radius:10px}
  .ams-sp .sp-search-panel>label{font-size:12.5px;margin:0}
  .ams-sp .sp-search-line{gap:6px}
  .ams-sp .sp-search-line input{min-height:42px;margin-top:5px;padding:7px 9px}
  .ams-sp .sp-search-line button{min-height:42px;margin-top:5px;padding:7px 9px;font-size:12px}
  .ams-sp .sp-examples,.ams-sp #sp-search-help{display:none}
  .ams-sp .sp-filter-line{display:block;margin-top:7px}
  .ams-sp .sp-filter-line label{font-size:11.5px}
  .ams-sp .sp-filter-line select{margin-top:3px;min-height:39px;font-size:14px}
  .ams-sp #sp-count{display:none}
  .ams-sp .sp-layout{order:2;display:flex;flex-direction:column;gap:7px;margin:0}
  .ams-sp .sp-results-toggle{order:0;display:flex;width:100%;align-items:center;gap:8px;min-height:43px;border:1px solid #c9dce6;border-radius:9px;background:#edf7fa;color:#17657c;text-align:left;padding:8px 12px;font-size:12.5px}
  .ams-sp .sp-results-toggle small{margin-left:auto;color:#547e90;font-size:11.5px}
  .ams-sp .sp-results-toggle span:last-child{font-size:18px;line-height:1}
  .ams-sp .sp-detail{order:1;padding:12px 13px;border-radius:10px;min-height:210px}
  .ams-sp .sp-results-panel{order:2;display:none;padding:9px;max-height:320px;overflow:auto}
  .ams-sp .sp-layout.is-results-expanded .sp-results-panel{order:1;display:block}
  .ams-sp .sp-layout.is-results-expanded .sp-detail{order:2}
  .ams-sp .sp-results-panel>h2{display:none}
  .ams-sp .sp-result{padding:10px 11px;margin-bottom:5px}
  .ams-sp .sp-detail-top{margin-bottom:10px}
  .ams-sp .sp-detail-top h2{font-size:18px;line-height:1.35;margin:3px 0 5px}
  .ams-sp .sp-detail-top .sp-eyebrow{font-size:11px;margin:0}
  .ams-sp .sp-detail-top .sp-muted{display:none}
  .ams-sp .sp-empty{padding:22px 10px}
  .ams-sp .sp-empty>span{display:none}
  .ams-sp .sp-empty h2{font-size:17px;margin-bottom:7px}
  .ams-sp .sp-regimens{grid-template-columns:1fr;gap:8px;margin-bottom:8px}
  .ams-sp .sp-regimens>section{padding:11px 12px}
  .ams-sp .sp-regimens h3{font-size:14px;margin-bottom:5px}
  .ams-sp .sp-regimens p{font-size:14px;line-height:1.55}
  .ams-sp .sp-context{order:3;margin:0;padding:11px 12px}
  .ams-sp .sp-context>summary{font-size:13px}
  .ams-sp #sp-alerts{order:4}
  .ams-sp .sp-reference{order:5;margin:0;padding:11px 12px}
  .ams-sp noscript{order:0}
}